Mafiriji otentha kwambiri otsika kwambiri (Mafriji a ULT) amapangidwa kuti azisunga mosamala mankhwala, zitsanzo, katemera, erythrocyte, hemameba, DNA/RNA, mabakiteriya, mafupa, umuna, ndi zinthu zina zamoyo.Ku Nenwell, athumafiriji otsika kwambiriamakhala ndi kutentha kosiyanasiyana kuchokera ku -25 ℃ mpaka -164 ℃, kutentha kumatsika mwachangu mukatha kutsegulidwa, amafikira mafiriji osakanikirana ndi gasi, osagwiritsa ntchito mphamvu komanso osawononga chilengedwe kuti apereke zinthu zokhazikika komanso zoyenera.Kuphatikiza pa zosankha za kutentha, pali zosankha zambiri kuti zikwaniritse zosiyana zosungirako, miyeso ndi zina zofunika.Mitundu ingapo ya mafiriji ilipo kuti musankhe, mufiriji wowongoka wa ULT amalola kuti munthu alowe, magawo osungira amatha kusintha, ULT yapansi panthaka ndi mafiriji apamwamba kwambiri angakuthandizeni kusunga malo ngati muli ndi kagawo kakang'ono kogwirira ntchito, ndi chifuwa. Firiji ya ULT imakwanira zinthu zosagwiritsidwa ntchito pang'ono zomwe mungasunge ndikuzisunga kwa nthawi yayitali.Mafiriji athu otsika kwambiri &mafiriji azachipatalandizoyenera kugwiritsa ntchito zipatala, malo osungira magazi, malo opangira kafukufuku, malo odana ndi mliri ndi zina zotero.